MRP-S27 Polyclonal Antibody

Ab type

Primary antibody

Background

28S ribosomal protein S27 mitochondrial (mitochondrial ribosomal protein S27) is encoded by nuclear genes MRPS27 and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that may be a functional partner of the death associated protein 3 (DAP3). Alternative splicing results in multiple transcript variants encoding different isoforms.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human MRPS27. AA range:16-65

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

47669

synonyms

MRPS27; KIAA0264; 28S ribosomal protein S27; mitochondrial; MRP-S27; S27mt