MRP-S24 Polyclonal Antibody

Ab type

Primary antibody

Background

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPS24 (mitochondrial ribosomal protein S24) encodes a 28S subunit protein. A pseudogene corresponding to MRPS24 is found on chromosome 11. Read-through transcription exists between MRPS24 and the upstream upregulator of cell proliferation (URGCP) gene.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human MRPS24. AA range:51-100

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

19015

synonyms

MRPS24; HSPC335; 28S ribosomal protein S24; mitochondrial; MRP-S24; S24mt; bMRP-47; bMRP47