MRP-L50 Polyclonal Antibody

Ab type

Primary antibody

Background

Mammalian mitochondrial ribosomal protein L 50 (39S ribosomal protein L50 mitochondrial) is encoded by nuclear gene MRPL50 and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human MRPL50. AA range:109-158

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

18325

synonyms

MRPL50; 39S ribosomal protein L50; mitochondrial; L50mt; MRP-L50