MPZL1 Antibody, HRP conjugated

Size

100ug

Clone Number

Aliases

MPZL1 antibody; PZR antibody; UNQ849/PRO1787 antibody; Myelin protein zero-like protein 1 antibody; Protein zero-related antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O95297

Immunogen

Recombinant Human Myelin protein zero-like protein 1 protein (195-258AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

HRP

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MPZL1

Research Areas

Signal transduction