ABCbiolab
SKU:ABCCS00476
MMP12 Antibody
MMP12 Antibody
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Size
100ul
Clone Number
2G3
Aliases
Macrophage metalloelastase (MME) (EC 3.4.24.65) (Macrophage elastase) (ME) (hME) (Matrix metalloproteinase-12) (MMP-12), MMP12, HME
Immunogen Species
Homo sapiens (Human)
UniProt ID
P39900
Immunogen
A synthesized peptide derived from human MMP12
Raised in
Species Reactivity
Human
Tested Applications
ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200
Background
May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
Clonality
Monoclonal
Isotype
Rabbit IgG
Purification Method
Affinity-chromatography
Conjugate
Non-conjugated
Buffer
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Liquid
Stroage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names
MMP12
Research Areas
Cancer; Cardiovascular; Signal transduction
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