MLH1 Polyclonal Antibody

Ab type

Primary antibody

Background

MLH1 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E.coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human MLH1. AA range:441-490

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

84601

synonyms

MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1