MIP Antibody

Size

100ug

Clone Number

Aliases

AQP 0 antibody; AQP0 antibody; Aquaporin antibody; Aquaporin 0 antibody; Aquaporin-0 antibody; Aquaporin0 antibody; Lens fiber major intrinsic protein antibody; LIM 1 antibody; LIM1 antibody; Major intrinsic protein 26kD antibody; Major intrinsic protein of lens fiber antibody; MIP 26 antibody; mip antibody; MIP_HUMAN antibody; MIP26 antibody; MP 26 antibody; MP26 antibody; PALM antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P30301

Immunogen

Recombinant Human Lens fiber major intrinsic protein (220-263AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

Background

Water channel (PubMed:24120416). Channel activity is down-regulated by CALM when cytoplasmic Ca(2+) levels are increased. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core (By similarity). Plays a role in cell-to-cell adhesion and facilitates gap junction coupling (PubMed:24120416).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MIP

Research Areas

Neuroscience; Metabolism; Signal transduction