MICB Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells| CD8 alphabeta T cells| and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however| it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human MICB

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

MICB; MHC class I polypeptide-related sequence B; MIC-B