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ABCbiolab
SKU:ABCB03430
MIB1 Polyclonal Antibody
MIB1 Polyclonal Antibody
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$275.00 USD
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Ab type
Primary antibody
Background
MIB1 (mindbomb E3 ubiquitin protein ligase 1) encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).
Reactivity
Human;Mouse;Rat
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Immunogen
Synthetic peptide from human protein at AA range: 901-950
Storage Stability
-20°C for one year
Concentration
1 mg/ml
MolecularWeight_Da
110136
synonyms
MIB1 DIP1 KIAA1323 ZZANK2
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