MIA Polyclonal Antibody

Ab type

Primary antibody

Background

The product of CHD4 belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthetic peptide from human protein at AA range: 90-131

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

217991

synonyms

Melanoma-derived growth regulatory protein (Melanoma inhibitory activity protein)