MGT5A Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene belongs to the glycosyltransferase family. It catalyzes the addition of beta-1,6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the activity of this enzyme has been correlated with the progression of invasive malignancies.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human protein . at AA range: 551-600

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A ;EC 2.4.1.155;Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase;GlcNAc-T V;GNT-V;Mannoside acetylglucosaminyltran