METAP2 Antibody

Size

100ug

Clone Number

Aliases

A930035J23Rik antibody; AI047573 antibody; AL024412 antibody; Amp2 antibody; AU014659; antibody; EIF 2 associated p67 homolog antibody; EIF-2-associated p67 antibody; Initiation factor 2 associated 67 kDa glycoprotein antibody; Initiation factor 2-associated 67 kDa glycoprotein antibody; MAP 2 antibody; MAP2 antibody; MAP2_HUMAN antibody; MetAP 2 antibody; Metap2 antibody; Methionine aminopeptidase 2 antibody; Methionyl aminopeptidase 2 antibody; MGC102452 antibody; MGC127390 antibody; MGC53792 antibody; MNPEP antibody; p67 antibody; p67eIF2 antibody; Peptidase M antibody; Peptidase M2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P50579

Immunogen

Recombinant Human Methionine aminopeptidase 2 protein (313-449AA)

Raised in

Rabbit

Species Reactivity

Human, Rat

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

METAP2

Research Areas

Metabolism; Signal transduction