Mesothelin Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a preproprotein that is proteolytically processed to generate two protein products| megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas| ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants| at least one of which encodes an isoform that is proteolytically processed.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human Mesothelin

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

69300

synonyms

Mesothelin; Mesothelin; CAK1 antigen; Pre-pro-megakaryocyte-potentiating factor; Megakaryocyte-potentiating factor; MPF; Mesothelin; cleaved form;