MER/TYRO3(Phospho-Tyr753/Tyr685) Polyclonal Antibody

Ab type

Primary antibody

Background

This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized phospho-peptide around the phosphorylation site of human MER/TYRO3 (Phospho-Tyr753/Tyr685)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

110249;96905

synonyms

c-mer proto-oncogene tyrosine kinase; MERTK MER