MEOX2 Antibody

Size

100ug

Clone Number

Aliases

GAX antibody; Growth arrest-specific homeobox antibody; Homeobox protein MOX 2 antibody; Homeobox protein MOX-2 antibody; meox2 antibody; MEOX2_HUMAN antibody; Mesenchyme homeobox 2 antibody; MOX2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P50222

Immunogen

Recombinant Human Homeobox protein MOX-2 protein (94-193AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development (By similarity). Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner (PubMed:22206000). May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MEOX2

Research Areas

Neuroscience; Cardiovascular