Menin Polyclonal Antibody

Ab type

Primary antibody

Background

MEN1 encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human MEN1. AA range:181-230

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

67993

synonyms

MEN1; SCG2; Menin