MEK Kinase-1 Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by MAP3K1 (mitogen-activated protein kinase kinase kinase 1) is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from MEK Kinase-1 . at AA range: 1340-1420

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

161289

synonyms

mitogen-activated protein kinase kinase kinase 1