MEGF10 Antibody, HRP conjugated

Size

100ug

Clone Number

Aliases

MEGF10 antibody; KIAA1780Multiple epidermal growth factor-like domains protein 10 antibody; Multiple EGF-like domains protein 10 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q96KG7

Immunogen

Recombinant Human Multiple epidermal growth factor-like domains protein 10 protein (123-314AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Membrane receptor involved in phagocytosis by macrophages of apoptotic cells. Cooperates with ABCA1 within the process of engulfment. Promotes the formation of large intracellular vacuoles and may be responsible for the uptake of amyloid-beta peptides. May also function in the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements. May play role in cell adhesion and motility. Is also an essential factor in the regulation of myogenesis. Controls the balance between skeletal muscle satellite cells proliferation and differentiation problably through regulation of the notch signaling pathway.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

HRP

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MEGF10

Research Areas

Others