MEF2D Antibody

Size

100ug

Clone Number

Aliases

DKFZp686I1536 antibody; MADS box transcription factor 2 polypeptide D antibody; Mef2d antibody; MEF2D_HUMAN antibody; Myocyte enhancer factor 2D antibody; Myocyte specific enhancer factor 2, polypeptide D antibody; Myocyte specific enhancer factor 2D antibody; Myocyte-specific enhancer factor 2D antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q14814

Immunogen

Recombinant Human Myocyte-specific enhancer factor 2D protein (299-509AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500

Background

Transcriptional activator which binds specifically to the MEF2 element, 5\\\'-YTA[AT](4)TAR-3\\\', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MEF2D

Research Areas

Epigenetics and Nuclear Signaling; Neuroscience; Cardiovascular