ABCbiolab
SKU:ABCB03374
MEF-2D Polyclonal Antibody
MEF-2D Polyclonal Antibody
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Ab type
Primary antibody
Background
MEF2D is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants.
Reactivity
Human;Mouse;Rat
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Immunogen
The antiserum was produced against synthesized peptide derived from human MEF2D. AA range:410-459
Storage Stability
-20°C for one year
Concentration
1 mg/ml
MolecularWeight_Da
55938
synonyms
MEF2D; Myocyte-specific enhancer factor 2D
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