MED31 Antibody

Size

100ug

Clone Number

Aliases

MED31 antibody; SOH1 antibody; CGI-125 antibody; Mediator of RNA polymerase II transcription subunit 31 antibody; Mediator complex subunit 31 antibody; Mediator complex subunit SOH1 antibody; hSOH1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y3C7

Immunogen

Recombinant Human Mediator of RNA polymerase II transcription subunit 31 protein (2-72AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MED31

Research Areas

Epigenetics and Nuclear Signaling