MED23 Antibody

Size

100ug

Clone Number

Aliases

130 kDa transcriptional co activator antibody; 133 kDa transcriptional co activator antibody; Activator recruited cofactor 130 kDa component antibody; Activator-recruited cofactor 130 kDa component antibody; ARC 130 antibody; ARC130 antibody; Cofactor required for Sp1 transcriptional activation subunit 3 130kDa antibody; Cofactor required for Sp1 transcriptional activation subunit 3 130kDa mediator antibody; Cofactor required for Sp1 transcriptional activation subunit 3 antibody; CRSP 130 antibody; CRSP 130 kD subunit antibody; CRSP 133 antibody; CRSP 3 antibody; CRSP complex subunit 3 antibody; CRSP130 antibody; CRSP133 antibody; CRSP3 antibody; CRSP3 protein antibody; DKFZp434H0117 antibody; DRIP 130 antibody; DRIP130 antibody; hSur-2 antibody; KIAA1216 antibody; MED 23 antibody; med23 antibody; MED23_HUMAN antibody; Mediator complex subunit 23 antibody; Mediator of RNA polymerase II transcription subunit 23 antibody; MRT18 antibody; Protein sur-2 homolog antibody; SUR 2 antibody; SUR2 antibody; Transcriptional co activator CRSP 130 antibody; Transcriptional co activator CRSP130 antibody; Transcriptional coactivator CRSP130 antibody; Vitamin D3 receptor interacting protein antibody; Vitamin D3 receptor interacting protein complex 130 kDa component antibody; Vitamin D3 receptor-interacting protein complex 130 kDa component antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9ULK4

Immunogen

Recombinant Human Mediator of RNA polymerase II transcription subunit 23 protein (1014-1368AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Required for transcriptional activation subsequent to the assembly of the pre-initiation complex (By similarity). Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. Required for transcriptional activation by adenovirus E1A protein. Required for ELK1-dependent transcriptional activation in response to activated Ras signaling.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MED23

Research Areas

Epigenetics and Nuclear Signaling; Signal transduction