MECP2 Antibody

Size

100ul

Clone Number

Aliases

AUTSX 3 antibody; AUTSX3 antibody; DKFZp686A24160 antibody; Mbd 5 antibody; Mbd5 antibody; MECP 2 antibody; MeCP 2 protein antibody; MeCP-2 protein antibody; Mecp2 antibody; MECP2_HUMAN antibody; Methyl CpG binding protein 2 (Rett syndrome) antibody; Methyl CpG binding protein 2 antibody; Methyl-CpG-binding protein 2 antibody; MRX 16 antibody; MRX 79 antibody; MRX16 antibody; MRX79 antibody; MRXS 13 antibody; MRXS13 antibody; MRXSL antibody; PPMX antibody; RS antibody; RTS antibody; RTT antibody; WBP 10 antibody; WBP10 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P51608

Immunogen

Recombinant Human Methyl-CpG-binding protein 2 protein (1-280AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC) (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MECP2

Research Areas

Epigenetics and Nuclear Signaling; Neuroscience