MECOM Antibody

Size

100ug

Clone Number

Aliases

MECOM antibody; EVI1 antibody; MDS1 antibody; PRDM3 antibody; Histone-lysine N-methyltransferase MECOM antibody; EC 2.1.1.- antibody; Ecotropic virus integration site 1 protein homolog antibody; EVI-1 antibody; MDS1 and EVI1 complex locus protein antibody; Myelodysplasia syndrome 1 protein antibody; Myelodysplasia syndrome-associated protein 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q03112

Immunogen

Recombinant Human Histone-lysine N-methyltransferase MECOM protein (534-632AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:500-1:1000

Background

Functions as a transcriptional regulator binding to DNA sequences in the promoter region of target genes and regulating positively or negatively their expression. Oncogene which plays a role in development, cell proliferation and differentiation. May also play a role in apoptosis through regulation of the JNK and TGF-beta signaling. Involved in hematopoiesis.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MECOM

Research Areas

Epigenetics and Nuclear Signaling