MEAF6 Antibody, FITC conjugated

Size

100ug

Clone Number

Aliases

MEAF6 antibody; C1orf149 antibody; CENP-28 antibody; EAF6Chromatin modification-related protein MEAF6 antibody; MYST/Esa1-associated factor 6 antibody; Esa1-associated factor 6 homolog antibody; Protein EAF6 homolog antibody; hEAF6 antibody; Sarcoma antigen NY-SAR-91 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9HAF1

Immunogen

Recombinant Human Chromatin modification-related protein MEAF6 protein (113-174AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

Background

Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

FITC

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MEAF6

Research Areas

Epigenetics and Nuclear Signaling