ME2 Polyclonal Antibody

Ab type

Primary antibody

Background

ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human ME2. AA range:201-250

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

65444

synonyms

ME2; NAD-dependent malic enzyme; mitochondrial; NAD-ME; Malic enzyme 2