MDM4 Antibody

Size

100ug

Clone Number

Aliases

DKFZp781B1423 antibody; Double minute 4 antibody; Double minute 4 human homolog of p53 binding protein antibody; Double minute 4 protein antibody; HDMX antibody; MDM 4 antibody; Mdm2 like p53 binding protein antibody; Mdm2-like p53-binding protein antibody; MDM4 antibody; Mdm4 p53 binding protein homolog mouse antibody; Mdm4 protein antibody; MDM4 related protein 1 antibody; Mdm4 transformed 3T3 cell double minute 4 antibody; Mdm4 transformed 3T3 cell double minute 4 p53 binding protein antibody; Mdm4 transformed 3T3 cell double minute 4 p53 binding protein mouse antibody; MDM4_HUMAN antibody; Mdmx protein antibody; MGC132766 antibody; Mouse double minute 4 homolog antibody; Mouse double minute 4 human homolog of p53 binding protein antibody; MRP 1 antibody; MRP1 antibody; p53 binding protein antibody; p53 BINDING PROTEIN MDM4 antibody; p53-binding protein Mdm4 antibody; Protein Mdm4 antibody; Protein Mdmx antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O15151

Immunogen

Recombinant Human Protein Mdm4 protein (208-306AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MDM4

Research Areas

Epigenetics and Nuclear Signaling; Cancer; Cell biology; Metabolism