MDFI Polyclonal Antibody

Ab type

Primary antibody

Background

MyoD family inhibitor is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human MDFI. AA range:103-152

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

25029

synonyms

MDFI; MyoD family inhibitor; Myogenic repressor I-mf