MCUB Antibody

Size

100ug

Clone Number

Aliases

MCUB antibody; CCDC109BCalcium uniporter regulatory subunit MCUb antibody; mitochondrial antibody; MCUb antibody; Coiled-coil domain-containing protein 109B antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NWR8

Immunogen

Recombinant Human Calcium uniporter regulatory subunit MCUb, mitochondrial protein (89-219AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MCUB

Research Areas

Others