MCRS1 Antibody

Size

100ug

Clone Number

Aliases

58 kDa microspherule protein antibody; Cell cycle regulated factor (78 kDa) antibody; Cell cycle regulated factor p78 antibody; Cell cycle-regulated factor p78 antibody; ICP22BP antibody; INO80 complex subunit J antibody; MCRS 1 antibody; MCRS 2 antibody; MCRS1 antibody; MCRS1_HUMAN antibody; MCRS2 antibody; Microspherule protein 1 antibody; MSP 58 antibody; MSP58 antibody; p78 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q96EZ8

Immunogen

Recombinant Human Microspherule protein 1 protein (1-138AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus (PubMed:11948183). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852). Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity (PubMed:15044100). Binds to G-quadruplex structures in mRNA (PubMed:16571602). Binds to RNA homopolymer poly(G) and poly(U) (PubMed:16571602).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MCRS1

Research Areas

Epigenetics and Nuclear Signaling