MCM10 Antibody

Size

100ul

Clone Number

Aliases

CNA43 antibody; DNA43 antibody; FLJ31133 antibody; Homolog of yeast MCM10 antibody; HsMCM10 antibody; mcm10 antibody; MCM10 minichromosome maintenance deficient 10 antibody; MCM10_HUMAN antibody; Minichromosome maintenance 10 replication initiation factor antibody; Minichromosome maintenance complex component 10 antibody; Minichromosome maintenance protein 10 isoform 1 antibody; PRO2249 antibody; Protein MCM10 homolog antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q7L590

Immunogen

Recombinant Human Protein MCM10 homolog protein (616-875AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, plays a role in preventing DNA damage during replication. Key effector of the RBBP6 and ZBTB38-mediated regulation of DNA-replication and common fragile sites stability; acts as a direct target of transcriptional repression by ZBTB38 (PubMed:24726359).

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MCM10

Research Areas

Epigenetics and Nuclear Signaling