MCAD Polyclonal Antibody

Ab type

Primary antibody

Background

ACADM encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human MCAD. AA range:134-183

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

46588

synonyms

ACADM; Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; MCAD