MAX(Phospho Ser11) Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members| which include Mad| Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation| differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human MAX (Phospho Ser11)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

17600

synonyms

MAX ;Phospho Ser11; Protein max; Class D basic helix-loop-helix protein 4; bHLHd4; Myc-associated factor X