MAS1 Antibody

Size

100ul

Clone Number

Aliases

MAS antibody; MAS proto oncogene antibody; Mas-related G protein-coupled receptor A antibody; MAS_HUMAN antibody; Mas1 antibody; MAS1 oncogene antibody; MAS1 proto-oncogene; G protein-coupled receptor antibody; MGRA antibody; Proto-oncogene Mas antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P04201

Immunogen

Recombinant Human Proto-oncogene Mas protein (246-325AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MAS1

Research Areas

Cancer; Cell biology; Signal transduction