MARK4 Polyclonal Antibody

Ab type

Primary antibody

Background

MARK4 (microtubule affinity regulating kinase 4) encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of MARK4 is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of MARK4 are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for MARK4.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human MARK4. AA range:461-510

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

82520

synonyms

MARK4; KIAA1860; MARKL1; MAP/microtubule affinity-regulating kinase 4; MAP/microtubule affinity-regulating kinase-like 1