MARCKSL1 Antibody

Size

100ul

Clone Number

Aliases

F52 antibody; Mac MARCKS antibody; Mac-MARCKS antibody; MacMARCKS antibody; Macrophage enriched Myristoylated Alanine Rich C Kinase Substrate Like Protein antibody; Macrophage myristoylated alanine-rich C kinase substrate antibody; MARCKS like 1 antibody; MARCKS like protein 1 antibody; MARCKS related protein antibody; MARCKS-like protein 1 antibody; MARCKS-related protein antibody; MARCKSL1 antibody; MLP antibody; MLP1 antibody; MRP antibody; MRP_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P49006

Immunogen

Recombinant Human MARCKS-related protein (1-195AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May also affect cancer cell migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MARCKSL1

Research Areas

Signal transduction