MARCKS(Phospho-Ser167/170) Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane| leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility| phagocytosis| membrane trafficking and mitogenesis.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized phosho peptide around human MARCKS (Ser167 and 170)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

MARCKS ;Ser167/170 ; Myristoylated alanine-rich C-kinase substrate; MARCKS; Protein kinase C substrate; 80 kDa protein; light chain; 80K-L protein; PKCSL