MAP1LC3B Antibody

Size

100ug

Clone Number

Aliases

ATG8F antibody; Autophagy-related protein LC3 B antibody; Autophagy-related ubiquitin-like modifier LC3 B antibody; LC3B antibody; LC3II antibody; MAP1 light chain 3 like protein 2 antibody; MAP1 light chain 3-like protein 2 antibody; MAP1A/1BLC3 antibody; MAP1A/MAP1B LC3 B antibody; MAP1A/MAP1B light chain 3 B antibody; MAP1ALC3 antibody; MAP1LC3B a antibody; Map1lc3b antibody; Microtubule associated protein 1 light chain 3 beta antibody; Microtubule-associated protein 1 light chain 3 beta antibody; Microtubule-associated proteins 1A/1B light chain 3B antibody; MLP3B_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9GZQ8

Immunogen

Recombinant Human Microtubule-associated proteins 1A/1B light chain 3B protein (2-100AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MAP1LC3B

Research Areas

Neuroscience; Cancer; Cardiovascular; Metabolism; Signal transduction