MAGED1 Antibody

Size

100ul

Clone Number

Aliases

DLXIN 1 antibody; MAGD1_HUMAN antibody; MAGE D1 antigen antibody; MAGE tumor antigen CCF antibody; MAGE-D1 antigen antibody; Maged1 antibody; Melanoma antigen family D 1 antibody; Melanoma associated antigen D1 antibody; Melanoma-associated antigen D1 antibody; Neurotrophin receptor interacting MAGE homolog antibody; Neurotrophin receptor-interacting MAGE homolog antibody; NRAGE antibody; PP2250 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y5V3

Immunogen

Recombinant Human Melanoma-associated antigen D1 protein (579-778AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MAGED1

Research Areas

Cell biology