MAGEA3 Antibody, FITC conjugated

Size

100ug

Clone Number

Aliases

Antigen MZ2 D antibody; Antigen MZ2-D antibody; Cancer/testis antigen 1.3 antibody; Cancer/testis antigen family 1 member 3 antibody; CT1.3 antibody; HIP8 antibody; HYPD antibody; MAGA3_HUMAN antibody; MAGE 3 antigen antibody; MAGE family member A3 antibody; MAGE-3 antigen antibody; MAGE3 antibody; MAGEA3 antibody; MAGEA6 antibody; Melanoma antigen family A 3 antibody; Melanoma associated antigen 3 antibody; Melanoma-associated antigen 3 antibody; MGC1461 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P43357

Immunogen

Recombinant Human Melanoma-associated antigen 3 protein (2-104AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

Background

Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

FITC

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MAGEA3

Research Areas

Cancer; Tags & Cell Markers; Immunology