MAD2L1 Antibody

Size

100ul

Clone Number

Aliases

HsMAD2 antibody; MAD 2 antibody; MAD2 like 1 antibody; MAD2 mitotic arrest deficient like 1 antibody; MAD2-like protein 1 antibody; Mad2l1 antibody; MD2L1_HUMAN antibody; Mitotic arrest deficient 2-like protein 1 antibody; Mitotic spindle assembly checkpoint protein MAD2A antibody; REV7 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q13257

Immunogen

Recombinant Human Mitotic spindle assembly checkpoint protein MAD2A protein (1-205AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MAD2L1

Research Areas

Cancer; Cell biology