MACC1 Polyclonal Antibody

Ab type

Primary antibody

Background

MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al. 2009 [PubMed: 19098908]).

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human MACC1. AA range:411-460

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

96639

synonyms

MACC1; Metastasis-associated in colon cancer protein 1; SH3 domain-containing protein 7a5