M Antibody

Size

100ul

Clone Number

Aliases

M antibody; Matrix protein antibody

Immunogen Species

Vesicular stomatitis Indiana virus (strain Glasgow) (VSIV)

UniProt ID

P04876

Immunogen

Recombinant Vesicular stomatitis Indiana virus Matrix protein (1-237AA)

Raised in

Rabbit

Species Reactivity

Vesicular stomatitis Indiana virus

Tested Applications

ELISA, WB; Recommended dilution: WB:1:1000-1:5000

Background

Plays a major role in assembly and budding of virion. Condensates the ribonucleocapsid core during virus assembly. Shut off cellular transcription by inhibiting mRNA nuclear export through direct interaction with host RAE1-NUP98 complex. This shut off presumably inhibit interferon signaling and thus establishment of antiviral state in virus infected cells. Induces cell-rounding, cytoskeleton disorganization and apoptosis in infected cell (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

M

Research Areas

Others