LUCA15 Polyclonal Antibody

Ab type

Primary antibody

Background

RBM5 is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. RNA-binding protein 5 plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. RBM5 is located within the tumor suppressor region 3p21. , and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human RBM5. AA range:226-275

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

92154

synonyms

RBM5; H37; LUCA15; RNA-binding protein 5; Protein G15; Putative tumor suppressor LUCA15; RNA-binding motif protein 5; Renal carcinoma antigen NY-REN-9