LTN1 Antibody

Size

100ug

Clone Number

Aliases

LTN1 antibody; C21orf10 antibody; C21orf98 antibody; KIAA0714 antibody; RNF160 antibody; ZNF294 antibody; HSPC087E3 ubiquitin-protein ligase listerin antibody; EC 2.3.2.27 antibody; RING finger protein 160 antibody; RING-type E3 ubiquitin transferase listerin antibody; Zinc finger protein 294 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O94822

Immunogen

Recombinant Human E3 ubiquitin-protein ligase listerin protein (462-591AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:23685075, PubMed:25132172, PubMed:25578875). Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

LTN1

Research Areas

Cell biology