LRWD1 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition| the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases| which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human LRWD1

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

71170

synonyms

LRWD1