LRIG1 Polyclonal Antibody

Ab type

Primary antibody

Background

The LRRs and the Ig-domains are each sufficient for EGFR/ERBB1 binding. This interaction is abolished only when these two domains are deleted.,Act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.,induction:By EGF.,Contains 17 LRR (leucine-rich) repeats.,Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with EGFR/ERBB1, ERBB2, ERBB3 and ERBB4.,tissue specificity:Widely expressed.,

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from part region of human protein

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Leucine-rich repeats and immunoglobulin-like domains protein 1 ;LIG-1