LRAT Antibody

Size

100ul

Clone Number

Aliases

LCA14 antibody; Lecithin retinol acyltransferase (phosphatidylcholine retinol O acyltransferase) antibody; Lecithin retinol acyltransferase antibody; LRAT antibody; LRAT_HUMAN antibody; Phosphatidylcholine retinol O acyltransferase antibody; Phosphatidylcholine--retinol O-acyltransferase antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O95237

Immunogen

Recombinant Human Lecithin retinol acyltransferase protein (24-182AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB; Recommended dilution: WB:1:1000-1:5000

Background

Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters. Retinyl esters are storage forms of vitamin A. LRAT plays a critical role in vision. It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

LRAT

Research Areas

Neuroscience; Metabolism; Signal transduction