LPIN1 Antibody

Size

100ul

Clone Number

Aliases

EC=3.1.3.4 antibody; KIAA0188 antibody; Lipin-1 antibody; Lpin1 antibody; LPIN1_HUMAN antibody; PAP1 antibody; Phosphatidate phosphatase LPIN1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q14693

Immunogen

Recombinant Human Phosphatidate phosphatase LPIN1 protein (741-890AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A/PPARA to modulate lipid metabolism gene expression (By similarity). Is involved in adipocyte differentiation. May also be involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

LPIN1

Research Areas

Cancer; Cardiovascular; Cell biology; Metabolism; Signal transduction