LOK Polyclonal Antibody

Ab type

Primary antibody

Background

STK10 encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. Serine/threonine-protein kinase 10 can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. Serine/threonine-protein kinase 10 can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human STK10. AA range:491-540

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

112135

synonyms

STK10; LOK; Serine/threonine-protein kinase 10; Lymphocyte-oriented kinase